When I was looking for a place to stay in Antwerpen my friend recommended Room National. It's in the middle of the centre, its very nicely decorated en that creates a cosy atmosphere. The service was very good. We stayed in room 69.
In the morning we got breakfast served in the room and the host answered every question and gave us recommendations for a good restaurant for the evening.
The location is very good, you can walk to the cathedral but also to the shops. In one word, fantastic!